Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p153 | (1) | ICCBH2019

Long-term growth hormone treatment alters glucose metabolism in achondroplasia

Harada Daisuke , Kashiwagi Hiroko , Ueyama Kaoru , Oriyama Kyoko , Hanioka Yuki , Sakamoto Natsuko , Kondo Masafumi Izui Kawai , Nagamatsu Yuiko , Yamada Hiroyuki , Seino Yoshiki , Namba Noriyuki

Objective: To investigate the effect of growth hormone (GH) treatment on glucose metabolism in achondroplasia (ACH) patients.Patients and methods: Twenty-five GH-treated (0.35 mg/kg/week) ACH patients (10 males and 15 females) were included in this study. Oral glucose tolerance test (OGTT) was performed at three time points; ‘pre-treatment’ (age: 4.0±1.9 years), ‘post short-term treatment’ (age: 6.5±3.0 years), and ‘pos...